Non-filarial elephantiasis in the Mt. Elgon area (Kapchorwa District) of Uganda
Identifieur interne : 009E18 ( Main/Exploration ); précédent : 009E17; suivant : 009E19Non-filarial elephantiasis in the Mt. Elgon area (Kapchorwa District) of Uganda
Auteurs : Ambrose W. Onapa [Ouganda] ; Paul E. Simonsen [Danemark] ; Erling M. Pedersen [Danemark]Source :
- Acta Tropica [ 0001-706X ] ; 2001.
Descripteurs français
- KwdFr :
- Adolescent, Adulte, Adulte d'âge moyen, Animaux, Anopheles (parasitologie), Antigènes d'helminthe (sang), Enfant, Enfant d'âge préscolaire, Femelle, Filariose lymphatique (parasitologie), Filariose lymphatique (épidémiologie), Humains, Microfilaria (parasitologie), Mâle, Nourrisson, Ouganda (épidémiologie), Population rurale, Prévalence, Wuchereria bancrofti (immunologie), Wuchereria bancrofti (isolement et purification), Éléphantiasis (parasitologie), Éléphantiasis (sang), Éléphantiasis (épidémiologie), Études séroépidémiologiques, Études transversales.
- Wicri :
- geographic : Ouganda.
- MESH :
- immunologie : Wuchereria bancrofti.
- isolement et purification : Wuchereria bancrofti.
- parasitologie : Anopheles, Filariose lymphatique, Microfilaria, Éléphantiasis.
- sang : Antigènes d'helminthe, Éléphantiasis.
- épidémiologie : Filariose lymphatique, Ouganda, Éléphantiasis.
- Adolescent, Adulte, Adulte d'âge moyen, Animaux, Enfant, Enfant d'âge préscolaire, Femelle, Humains, Mâle, Nourrisson, Population rurale, Prévalence, Études séroépidémiologiques, Études transversales.
English descriptors
- KwdEn :
- Adolescent, Adult, Animals, Anopheles (parasitology), Antigens, Helminth (blood), Child, Child, Preschool, Cross-Sectional Studies, Elephantiasis, Elephantiasis (blood), Elephantiasis (epidemiology), Elephantiasis (parasitology), Elephantiasis, Filarial (epidemiology), Elephantiasis, Filarial (parasitology), Female, Filariasis, Humans, Infant, Male, Microfilariae (parasitology), Middle Aged, Podoconiosis, Prevalence, Rural Population, Seroepidemiologic Studies, Uganda, Uganda (epidemiology), Volcanic soils, Wuchereria bancrofti (immunology), Wuchereria bancrofti (isolation & purification).
- MESH :
- chemical , blood : Antigens, Helminth.
- blood : Elephantiasis.
- epidemiology : Elephantiasis, Elephantiasis, Filarial, Uganda.
- immunology : Wuchereria bancrofti.
- isolation & purification : Wuchereria bancrofti.
- parasitology : Anopheles, Elephantiasis, Elephantiasis, Filarial, Microfilariae.
- Adolescent, Adult, Animals, Child, Child, Preschool, Cross-Sectional Studies, Female, Humans, Infant, Male, Middle Aged, Prevalence, Rural Population, Seroepidemiologic Studies.
Abstract
Following reports of a high frequency of elephantiasis in Kwen County (Kapchorwa District) on the slopes of Mt. Elgon in Uganda, a baseline survey for lymphatic filariasis was carried out in three villages in the affected area. Individuals aged 1 year and above were examined for chronic manifestations of lymphatic filariasis, and for specific circulating filarial antigens and microfilariae of Wuchereria bancrofti. Elephantiasis was observed in all age groups from 10 years and above. The overall prevalence was 4.5%, and the prevalence among individuals aged ≥20 years was 8.2%. Males and females were equally affected. However, there were only few cases of hydrocele (overall prevalence in males of 1.0%) and blood examinations were negative for W. bancrofti circulating antigens and microfilariae. Sampling of potential filariasis mosquito vectors revealed low densities of Anopheles gambiae s.l. and An. funestus, and none of these were infected with filarial larvae. In view of the low hydrocele to elephantiasis ratio, the absence of filarial infection in humans and mosquitoes, the high altitude (1500–2200 m above sea level) and the volcanic soil type, it is concluded that elephantiasis seen in this area is not of filarial origin but most likely is due to podoconiosis (endemic non-filarial elephantiasis).
Url:
DOI: 10.1016/S0001-706X(00)00185-6
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: 002604
- to stream Istex, to step Curation: 002604
- to stream Istex, to step Checkpoint: 002B21
- to stream Main, to step Merge: 00A271
- to stream PubMed, to step Corpus: 004891
- to stream PubMed, to step Curation: 004891
- to stream PubMed, to step Checkpoint: 004891
- to stream Ncbi, to step Merge: 000557
- to stream Ncbi, to step Curation: 000557
- to stream Ncbi, to step Checkpoint: 000557
- to stream Main, to step Merge: 009E05
- to stream Main, to step Curation: 009E18
Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Non-filarial elephantiasis in the Mt. Elgon area (Kapchorwa District) of Uganda</title><author><name sortKey="Onapa, Ambrose W" sort="Onapa, Ambrose W" uniqKey="Onapa A" first="Ambrose W." last="Onapa">Ambrose W. Onapa</name></author><author><name sortKey="Simonsen, Paul E" sort="Simonsen, Paul E" uniqKey="Simonsen P" first="Paul E." last="Simonsen">Paul E. Simonsen</name></author><author><name sortKey="Pedersen, Erling M" sort="Pedersen, Erling M" uniqKey="Pedersen E" first="Erling M." last="Pedersen">Erling M. Pedersen</name></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:527D0E20DD8637577529D686D327B217DAC733C8</idno><date when="2001" year="2001">2001</date><idno type="doi">10.1016/S0001-706X(00)00185-6</idno><idno type="url">https://api.istex.fr/document/527D0E20DD8637577529D686D327B217DAC733C8/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">002604</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">002604</idno><idno type="wicri:Area/Istex/Curation">002604</idno><idno type="wicri:Area/Istex/Checkpoint">002B21</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Checkpoint">002B21</idno><idno type="wicri:doubleKey">0001-706X:2001:Onapa A:non:filarial:elephantiasis</idno><idno type="wicri:Area/Main/Merge">00A271</idno><idno type="wicri:source">PubMed</idno><idno type="RBID">pubmed:11230827</idno><idno type="wicri:Area/PubMed/Corpus">004891</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">004891</idno><idno type="wicri:Area/PubMed/Curation">004891</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">004891</idno><idno type="wicri:Area/PubMed/Checkpoint">004891</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">004891</idno><idno type="wicri:Area/Ncbi/Merge">000557</idno><idno type="wicri:Area/Ncbi/Curation">000557</idno><idno type="wicri:Area/Ncbi/Checkpoint">000557</idno><idno type="wicri:doubleKey">0001-706X:2001:Onapa A:non:filarial:elephantiasis</idno><idno type="wicri:Area/Main/Merge">009E05</idno><idno type="wicri:Area/Main/Curation">009E18</idno><idno type="wicri:Area/Main/Exploration">009E18</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Non-filarial elephantiasis in the Mt. Elgon area (Kapchorwa District) of Uganda</title><author><name sortKey="Onapa, Ambrose W" sort="Onapa, Ambrose W" uniqKey="Onapa A" first="Ambrose W." last="Onapa">Ambrose W. Onapa</name><affiliation wicri:level="1"><country xml:lang="fr">Ouganda</country><wicri:regionArea>Vector Control Division, Ministry of Health, PO Box 1661, Kampala</wicri:regionArea><wicri:noRegion>Kampala</wicri:noRegion></affiliation></author><author><name sortKey="Simonsen, Paul E" sort="Simonsen, Paul E" uniqKey="Simonsen P" first="Paul E." last="Simonsen">Paul E. Simonsen</name><affiliation wicri:level="1"><country wicri:rule="url">Danemark</country></affiliation><affiliation wicri:level="1"><country xml:lang="fr">Danemark</country><wicri:regionArea>Danish Bilharziasis Laboratory, Jaegersborg Alle 1 D, 2920 Charlottenlund</wicri:regionArea><wicri:noRegion>2920 Charlottenlund</wicri:noRegion></affiliation></author><author><name sortKey="Pedersen, Erling M" sort="Pedersen, Erling M" uniqKey="Pedersen E" first="Erling M." last="Pedersen">Erling M. Pedersen</name><affiliation wicri:level="1"><country xml:lang="fr">Danemark</country><wicri:regionArea>Danish Bilharziasis Laboratory, Jaegersborg Alle 1 D, 2920 Charlottenlund</wicri:regionArea><wicri:noRegion>2920 Charlottenlund</wicri:noRegion></affiliation></author></analytic><monogr></monogr><series><title level="j">Acta Tropica</title><title level="j" type="abbrev">ACTROP</title><idno type="ISSN">0001-706X</idno><imprint><publisher>ELSEVIER</publisher><date type="published" when="2001">2001</date><biblScope unit="volume">78</biblScope><biblScope unit="issue">2</biblScope><biblScope unit="page" from="171">171</biblScope><biblScope unit="page" to="176">176</biblScope></imprint><idno type="ISSN">0001-706X</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0001-706X</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adolescent</term><term>Adult</term><term>Animals</term><term>Anopheles (parasitology)</term><term>Antigens, Helminth (blood)</term><term>Child</term><term>Child, Preschool</term><term>Cross-Sectional Studies</term><term>Elephantiasis</term><term>Elephantiasis (blood)</term><term>Elephantiasis (epidemiology)</term><term>Elephantiasis (parasitology)</term><term>Elephantiasis, Filarial (epidemiology)</term><term>Elephantiasis, Filarial (parasitology)</term><term>Female</term><term>Filariasis</term><term>Humans</term><term>Infant</term><term>Male</term><term>Microfilariae (parasitology)</term><term>Middle Aged</term><term>Podoconiosis</term><term>Prevalence</term><term>Rural Population</term><term>Seroepidemiologic Studies</term><term>Uganda</term><term>Uganda (epidemiology)</term><term>Volcanic soils</term><term>Wuchereria bancrofti (immunology)</term><term>Wuchereria bancrofti (isolation & purification)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adolescent</term><term>Adulte</term><term>Adulte d'âge moyen</term><term>Animaux</term><term>Anopheles (parasitologie)</term><term>Antigènes d'helminthe (sang)</term><term>Enfant</term><term>Enfant d'âge préscolaire</term><term>Femelle</term><term>Filariose lymphatique (parasitologie)</term><term>Filariose lymphatique (épidémiologie)</term><term>Humains</term><term>Microfilaria (parasitologie)</term><term>Mâle</term><term>Nourrisson</term><term>Ouganda (épidémiologie)</term><term>Population rurale</term><term>Prévalence</term><term>Wuchereria bancrofti (immunologie)</term><term>Wuchereria bancrofti (isolement et purification)</term><term>Éléphantiasis (parasitologie)</term><term>Éléphantiasis (sang)</term><term>Éléphantiasis (épidémiologie)</term><term>Études séroépidémiologiques</term><term>Études transversales</term></keywords><keywords scheme="MESH" type="chemical" qualifier="blood" xml:lang="en"><term>Antigens, Helminth</term></keywords><keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>Ouganda</term></keywords><keywords scheme="MESH" qualifier="blood" xml:lang="en"><term>Elephantiasis</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Elephantiasis</term><term>Elephantiasis, Filarial</term><term>Uganda</term></keywords><keywords scheme="MESH" qualifier="immunologie" xml:lang="fr"><term>Wuchereria bancrofti</term></keywords><keywords scheme="MESH" qualifier="immunology" xml:lang="en"><term>Wuchereria bancrofti</term></keywords><keywords scheme="MESH" qualifier="isolation & purification" xml:lang="en"><term>Wuchereria bancrofti</term></keywords><keywords scheme="MESH" qualifier="isolement et purification" xml:lang="fr"><term>Wuchereria bancrofti</term></keywords><keywords scheme="MESH" qualifier="parasitologie" xml:lang="fr"><term>Anopheles</term><term>Filariose lymphatique</term><term>Microfilaria</term><term>Éléphantiasis</term></keywords><keywords scheme="MESH" qualifier="parasitology" xml:lang="en"><term>Anopheles</term><term>Elephantiasis</term><term>Elephantiasis, Filarial</term><term>Microfilariae</term></keywords><keywords scheme="MESH" qualifier="sang" xml:lang="fr"><term>Antigènes d'helminthe</term><term>Éléphantiasis</term></keywords><keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Filariose lymphatique</term><term>Ouganda</term><term>Éléphantiasis</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adolescent</term><term>Adult</term><term>Animals</term><term>Child</term><term>Child, Preschool</term><term>Cross-Sectional Studies</term><term>Female</term><term>Humans</term><term>Infant</term><term>Male</term><term>Middle Aged</term><term>Prevalence</term><term>Rural Population</term><term>Seroepidemiologic Studies</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adolescent</term><term>Adulte</term><term>Adulte d'âge moyen</term><term>Animaux</term><term>Enfant</term><term>Enfant d'âge préscolaire</term><term>Femelle</term><term>Humains</term><term>Mâle</term><term>Nourrisson</term><term>Population rurale</term><term>Prévalence</term><term>Études séroépidémiologiques</term><term>Études transversales</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Following reports of a high frequency of elephantiasis in Kwen County (Kapchorwa District) on the slopes of Mt. Elgon in Uganda, a baseline survey for lymphatic filariasis was carried out in three villages in the affected area. Individuals aged 1 year and above were examined for chronic manifestations of lymphatic filariasis, and for specific circulating filarial antigens and microfilariae of Wuchereria bancrofti. Elephantiasis was observed in all age groups from 10 years and above. The overall prevalence was 4.5%, and the prevalence among individuals aged ≥20 years was 8.2%. Males and females were equally affected. However, there were only few cases of hydrocele (overall prevalence in males of 1.0%) and blood examinations were negative for W. bancrofti circulating antigens and microfilariae. Sampling of potential filariasis mosquito vectors revealed low densities of Anopheles gambiae s.l. and An. funestus, and none of these were infected with filarial larvae. In view of the low hydrocele to elephantiasis ratio, the absence of filarial infection in humans and mosquitoes, the high altitude (1500–2200 m above sea level) and the volcanic soil type, it is concluded that elephantiasis seen in this area is not of filarial origin but most likely is due to podoconiosis (endemic non-filarial elephantiasis).</div></front></TEI><affiliations><list><country><li>Danemark</li><li>Ouganda</li></country></list><tree><country name="Ouganda"><noRegion><name sortKey="Onapa, Ambrose W" sort="Onapa, Ambrose W" uniqKey="Onapa A" first="Ambrose W." last="Onapa">Ambrose W. Onapa</name></noRegion></country><country name="Danemark"><noRegion><name sortKey="Simonsen, Paul E" sort="Simonsen, Paul E" uniqKey="Simonsen P" first="Paul E." last="Simonsen">Paul E. Simonsen</name></noRegion><name sortKey="Pedersen, Erling M" sort="Pedersen, Erling M" uniqKey="Pedersen E" first="Erling M." last="Pedersen">Erling M. Pedersen</name><name sortKey="Simonsen, Paul E" sort="Simonsen, Paul E" uniqKey="Simonsen P" first="Paul E." last="Simonsen">Paul E. Simonsen</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/LymphedemaV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 009E18 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 009E18 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Sante
|area= LymphedemaV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= ISTEX:527D0E20DD8637577529D686D327B217DAC733C8
|texte= Non-filarial elephantiasis in the Mt. Elgon area (Kapchorwa District) of Uganda
}}
| This area was generated with Dilib version V0.6.31. |  |